Release date: 11 December 2025

TetraScience has released its next version of the Tetra Data Platform (TDP), version 4.4.1. To help customers better proactively monitor their data ingestion infrastructure, this release makes the new Alert Management page available by default. It also resolves a known issue that kept the TetraScience AI Services (limited availability release) page from loading in TDP v4.4.0.

Here are the details for what's new in TDP v4.4.1.

GxP Impact Assessment

All new TDP functionalities go through a GxP impact assessment to determine validation needs for GxP installations.

New Functionality items marked with an asterisk (*) address usability, supportability, or infrastructure issues, and do not affect Intended Use for validation purposes, per this assessment.

Enhancements and Bug Fixes do not generally affect Intended Use for validation purposes.

Items marked as either beta release or limited availability release (previously early adopter program (EAP)) are not validated for GxP by TetraScience. However, customers can use these prerelease features and components in production if they perform their own validation.

Notes

• Any blue NOTE blocks indicate helpful considerations, but don’t require customer action.

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NOTE

• Any yellow IMPORTANT note blocks indicate required actions that customers must take to either use a new functionality or enhancement, or to avoid potential issues during the upgrade.

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IMPORTANT

New Functionality

New functionalities are features that weren't previously available in the TDP.

• There's no new functionality in this release.

Enhancements

Enhancements are modifications to existing functionality that improve performance or usability, but don't alter the function or intended use of the system.

TDP System Administration Enhancements

Alert Management Page Is Now Activated by Default

To streamline the Alert Management page’s accessibility, it’s now activated for all customers by default. Previously, the page was optional and turned on by request only. The new page helps customers proactively monitor their data ingestion infrastructure.

To provide access to the Alert Management page, a new Operational Intelligence option appears in the left navigation menu, replacing the previous Health Monitoring option.

Choosing the new Operational Intelligence option from the left menu provides the option to select from either the Health Monitoring dashboard or the new Alert Management page.

For more information, see Alert Management.

Infrastructure Updates

There are no infrastructure updates in this release.

Bug Fixes

The following bugs are now fixed.

TDP System Administration Bug Fixes

• The AI Services (limited availability release) page now loads in TDP environments where it’s activated.
• The Data User policy now allows users who are assigned the policy to create saved searches.

Deprecated Features

There are no new deprecated features in this release.

For more information about TDP deprecations, see Tetra Product Deprecation Notices.

Known and Possible Issues

The following are known and possible issues for TDP v4.4.1.

Data Integrations Known Issues

• For new Tetra Agents set up through a Tetra Data Hub and a Generic Data Connector (GDC), Agent command queues aren’t enabled by default. However, the TDP UI still displays the command queue as enabled when it’s deactivated. As a workaround, customers can manually sync the Tetra Data Hub with the TDP. A fix for this issue is in development and testing and is scheduled for a future release.
• For on-premises standalone Connector deployments that use a proxy, the Connector’s installation script fails when the proxy’s name uses the following format: username:password@hostname. As a workaround, customers should contact their customer account leader to update the Connector’s install script. A fix for this issue is in development and testing and is scheduled for TDP v4.4.1.

Data Harmonization and Engineering Known Issues

• For customers using proxy servers to access the TDP, Tetraflow pipelines created in TDP v4.3.0 and earlier fail and return a CalledProcessError error. As a workaround, customers should disable any existing Tetraflow pipelines and then enable them again. A fix for this issue is in development and testing and is scheduled for a future release.
• The legacy ts-sdk put command to publish artifacts for Self-service pipelines (SSPs) returns a successful (0) status code, even if the command fails. As a workaround, customers should switch to using the latest TetraScience Command Line Interface (CLI) and run the ts-cli publish command to publish artifacts instead. A fix for this issue is in development and testing and is scheduled for a future ts-sdk release.
• IDS files larger than 2 GB are not indexed for search.
• The Chromeleon IDS (thermofisher_chromeleon) v6 Lakehouse tables aren't accessible through Snowflake Data Sharing. There are more subcolumns in the table’s method column than Snowflake allows, so Snowflake doesn’t index the table. A fix for this issue is in development and testing and is scheduled for a future release.
• Empty values in Amazon Athena SQL tables display as NULL values in Lakehouse tables.
• File statuses on the File Processing page can sometimes display differently than the statuses shown for the same files on the Pipelines page in the Bulk Processing Job Details dialog. For example, a file with an Awaiting Processing status in the Bulk Processing Job Details dialog can also show a Processing status on the File Processing page. This discrepancy occurs because each file can have different statuses for different backend services, which can then be surfaced in the TDP at different levels of granularity. A fix for this issue is in development and testing.
• Logs don’t appear for pipeline workflows that are configured with retry settings until the workflows complete.
• Files with more than 20 associated documents (high-lineage files) do not have their lineage indexed by default. To identify and re-lineage-index any high-lineage files, customers must contact their CSM to run a separate reconciliation job that overrides the default lineage indexing limit.
• OpenSearch index mapping conflicts can occur when a client or private namespace creates a backwards-incompatible data type change. For example: If doc.myField is a string in the common IDS and an object in the non-common IDS, then it will cause an index mapping conflict, because the common and non-common namespace documents are sharing an index. When these mapping conflicts occur, the files aren’t searchable through the TDP UI or API endpoints. As a workaround, customers can either create distinct, non-overlapping version numbers for their non-common IDSs or update the names of those IDSs.
• File reprocessing jobs can sometimes show fewer scanned items than expected when either a health check or out-of-memory (OOM) error occurs, but not indicate any errors in the UI. These errors are still logged in Amazon CloudWatch Logs. A fix for this issue is in development and testing.
• File reprocessing jobs can sometimes incorrectly show that a job finished with failures when the job actually retried those failures and then successfully reprocessed them. A fix for this issue is in development and testing.
• File edit and update operations are not supported on metadata and label names (keys) that include special characters. Metadata, tag, and label values can include special characters, but it’s recommended that customers use the approved special characters only. For more information, see Attributes.
• The File Details page sometimes displays an Unknown status for workflows that are either in a Pending or Running status. Output files that are generated by intermediate files within a task script sometimes show an Unknown status, too.
• Some historical protocols and IDSs are not compatible with the new ids-to-lakehouse data ingestion mechanism. The following protocols and IDSs are known to be incompatible with ids-to-lakehouse pipelines:
  • Protocol: fcs-raw-to-ids < v1.5.1 (IDS: flow-cytometer < v4.0.0)
  • Protocol: thermofisher-quantstudio-raw-to-ids < v5.0.0 (IDS: pcr-thermofisher-quantstudio < v5.0.0)
  • Protocol: biotek-gen5-raw-to-ids v1.2.0 (IDS: plate-reader-biotek-gen5 v1.0.1)
  • Protocol: nanotemper-monolith-raw-to-ids v1.1.0 (IDS: mst-nanotemper-monolith v1.0.0)
  • Protocol: ta-instruments-vti-raw-to-ids v2.0.0 (IDS: vapor-sorption-analyzer-tainstruments-vti-sa v2.0.0)

Data Access and Management Known Issues

• On the Search (Classic) page, shortcuts created in browse view also appear in collections and as saved searches when they shouldn’t.

• Saved Searches created on the Search (Classic) page can't be used or saved as Collections on the Search page.

• Data Apps won’t launch in customer-hosted environments if the private subnets where the TDP is deployed are restricted and don’t have outbound access to the internet. As a workaround, customers should enable the following AWS Interface VPC endpoint in the VPC that the TDP uses: com.amazonaws.<AWS REGION>.elasticfilesystem

• Data Apps return CORS errors in all customer-hosted deployments. As a workaround, customers should create an AWS Systems Manager (SSM) parameter using the following pattern: /tetrascience/production/ECS/ts-service-data-apps/DOMAIN

  For DOMAIN, enter your TDP URL without the https:// (for example, platform.tetrascience.com).

• The Data Lakehouse Architecture doesn't support restricted, customer-hosted environments that connect to the TDP through a proxy and have no connection to the internet. A fix for this issue is in development and testing and is scheduled for a future release.

• On the File Details page, related files links don't work when accessed through the Show all X files within this workflow option. As a workaround, customers should select the Show All Related Files option instead. A fix for this issue is in development and testing and is scheduled for a future release.

• When customers upload a new file on the Search page by using the Upload File button, the page doesn’t automatically update to include the new file in the search results. As a workaround, customers should refresh the Search page in their web browser after selecting the Upload File button. A fix for this issue is in development and testing and is scheduled for a future TDP release.

• Values returned as empty strings when running SQL queries on SQL tables can sometimes return Null values when run on Lakehouse tables. As a workaround, customers taking part in the Data Lakehouse Architecture EAP should update any SQL queries that specifically look for empty strings to instead look for both empty string and Null values.

• Query DSL queries run on indices in an OpenSearch cluster can return partial search results if the query puts too much compute load on the system. This behavior occurs because the OpenSearch search.default_allow_partial_result setting is configured as true by default. To help avoid this issue, customers should use targeted search indexing best practices to reduce query compute loads. A way to improve visibility into when partial search results are returned is currently in development and testing and scheduled for a future TDP release.

• Text within the context of a RAW file that contains escape (\) or other special characters may not always index completely in OpenSearch. A fix for this issue is in development and testing, and is scheduled for an upcoming release.

• If a data access rule is configured as [label] exists > OR > [same label] does not exist, then no file with the defined label is accessible to the Access Group. A fix for this issue is in development and testing and scheduled for a future TDP release.

• File events aren’t created for temporary (TMP) files, so they’re not searchable. This behavior can also result in an Unknown state for Workflow and Pipeline views on the File Details page.

• When customers search for labels in the TDP UI’s search bar that include either @ symbols or some unicode character combinations, not all results are always returned.

• The File Details page displays a 404 error if a file version doesn't comply with the configured Data Access Rules for the user.

TDP System Administration Known Issues

• The Data user policy doesn’t allow users who are assigned the policy to create saved searches, even though it should grant the required functionality permissions. A fix for this issue is scheduled for TDP v4.4.1.

• Limited availability release Data Retention Policies don’t consistently delete data. A fix for this issue is in development and testing and is scheduled for a future release.

• Failed files in the Data Lakehouse can’t be reprocessed through the Health Monitoring page. Instead, customers should monitor and reprocess failed Lakehouse files by using the Data Reconciliation, File Processing, or Workflow Processing pages.

• The latest Connector versions incorrectly log the following errors in Amazon CloudWatch Logs:

  • Error loading organization certificates. Initialization will continue, but untrusted SSL connections will fail.
  • Client is not initialized - certificate array will be empty
    These organization certificate errors have no impact and shouldn’t be logged as errors. A fix for this issue is currently in development and testing, and is scheduled for an upcoming release. There is no workaround to prevent Connectors from producing these log messages. To filter out these errors when viewing logs, customers can apply the following CloudWatch Logs Insights query filters when querying log groups. (Issue #2818)
    CloudWatch Logs Insights Query Example for Filtering Organization Certificate Errors

  fields @timestamp, @message, @logStream, @log
  | filter message != 'Error loading organization certificates. Initialization will continue, but untrusted SSL connections will fail.'
  | filter message != 'Client is not initialized - certificate array will be empty'
  | sort @timestamp desc
  | limit 20

• If a reconciliation job, bulk edit of labels job, or bulk pipeline processing job is canceled, then the job’s ToDo, Failed, and Completed counts can sometimes display incorrectly.

Upgrade Considerations

During the upgrade, there might be a brief downtime when users won't be able to access the TDP user interface and APIs.

After the upgrade, the TetraScience team verifies that the platform infrastructure is working as expected through a combination of manual and automated tests. If any failures are detected, the issues are immediately addressed, or the release can be rolled back. Customers can also verify that TDP search functionality continues to return expected results, and that their workflows continue to run as expected.

For more information about the release schedule, including the GxP release schedule and timelines, see the Product Release Schedule.

For more details on upgrade timing, customers should contact their customer account leader.

Security

TetraScience continually monitors and tests the TDP codebase to identify potential security issues. Various security updates are applied to the following areas on an ongoing basis:

• Operating systems
• Third-party libraries

Quality Management

TetraScience is committed to creating quality software. Software is developed and tested following the ISO 9001-certified TetraScience Quality Management System. This system ensures the quality and reliability of TetraScience software while maintaining data integrity and confidentiality.

Other Release Notes

To view other TDP release notes, see Tetra Data Platform Release Notes.